Pirfenidone 200 mg (Pirfenex)

What is Pirfenidone 200 mg (Pirfenex)?

Pirfenidone 200 mg (Pirfenex) is a medication used to treat idiopathic pulmonary fibrosis (IPF), a progressive and chronic lung disease that causes scarring of the lung tissue, leading to breathing difficulties. Pirfenidone is classified as an anti-fibrotic drug that helps slow the progression of fibrosis (scarring) in the lungs. It works by reducing inflammation and preventing the formation of excess collagen, a protein that contributes to scarring in the lungs. Pirfenidone is typically prescribed to patients with IPF to help improve lung function and quality of life.

How Does Pirfenidone 200 mg (Pirfenex) Work?

Pirfenidone works by inhibiting several pathways involved in fibrosis and inflammation. It acts as an anti-inflammatory and anti-fibrotic agent, which helps to reduce the production of collagen and other fibrotic tissues in the lungs. This mechanism helps prevent the progression of lung scarring, improving lung function and reducing symptoms such as shortness of breath and fatigue. By targeting the pathways involved in fibrosis, Pirfenidone helps to slow down the decline in lung function associated with IPF.

Benefits of Pirfenidone 200 mg (Pirfenex)

1. Slows the Progression of IPF: Pirfenidone is primarily used to slow the progression of idiopathic pulmonary fibrosis (IPF), helping to reduce the rate of lung function decline.
2. Improves Lung Function: By reducing the formation of fibrotic tissue in the lungs, Pirfenidone helps improve lung function and breathing capacity in patients with IPF.
3. Enhances Quality of Life: As a result of its action on reducing lung fibrosis, Pirfenidone can help improve the overall quality of life for individuals with IPF by alleviating symptoms like shortness of breath and fatigue.
4. Reduces Inflammation: Pirfenidone’s anti-inflammatory properties help reduce inflammation in the lungs, contributing to better lung health and function over time.

How to Take Pirfenidone 200 mg (Pirfenex)

• Dosage: The recommended starting dose of Pirfenidone 200 mg (Pirfenex) is usually 1 tablet three times a day (200 mg each) with meals. The dose may be gradually increased by your doctor based on your tolerance and medical condition.
• How to Take: Pirfenidone should be taken with food to reduce the risk of stomach upset. It is important to swallow the tablets whole and not crush or chew them.
• Missed Dose: If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed one.
• Regular Monitoring: While on Pirfenidone, your doctor may recommend regular monitoring of liver function and other health parameters to ensure the medication is working effectively and to detect any potential side effects early.

Note: Always follow your healthcare provider’s instructions regarding dosage and duration of treatment.

Who Makes Pirfenidone 200 mg (Pirfenex)?

Pirfenidone 200 mg (Pirfenex) is manufactured by Cipla Ltd., a leading global pharmaceutical company based in India. Cipla is known for producing high-quality generic medications and has a strong presence in the treatment of respiratory diseases, cancer, cardiovascular conditions, and more. Cipla’s commitment to providing affordable and effective healthcare solutions has made it a trusted name in the global pharmaceutical industry.

Is Pirfenidone 200 mg (Pirfenex) Safe for Humans?

Pirfenidone is generally safe for most people when taken as prescribed by a healthcare provider. However, it is important to follow your doctor’s instructions and inform them about any existing medical conditions, particularly:

• Liver or kidney disease: Pirfenidone can affect liver function, so people with liver issues should use it with caution.
• History of gastrointestinal issues: Pirfenidone can cause gastrointestinal side effects such as nausea, diarrhea, and indigestion.
• Pregnancy and breastfeeding: Pirfenidone should only be used during pregnancy if clearly needed and prescribed by a doctor. It is not recommended for breastfeeding mothers, as it may pass into breast milk.

Precautions: Regular liver function tests are necessary during treatment with Pirfenidone to ensure that the liver is functioning properly.

Side Effects of Pirfenidone 200 mg (Pirfenex)

Like all medications, Pirfenidone can cause side effects. Some common side effects include:

• Gastrointestinal issues: Nausea, diarrhea, loss of appetite, indigestion, or stomach pain.
• Fatigue: Some individuals may experience tiredness or weakness.
• Skin reactions: Rash, photosensitivity (increased sensitivity to sunlight), or itching.
• Liver issues: Elevated liver enzymes, which could indicate liver damage (requires monitoring).
• Dizziness: Some people may feel lightheaded or dizzy while on Pirfenidone.

Serious side effects are rare but may include severe liver problems, allergic reactions (swelling of the face, lips, or throat), or signs of infection. If you experience any of these symptoms, seek medical attention immediately.

Disclaimer

This information is for educational purposes only and does not replace professional medical advice. Always consult your healthcare provider before starting or stopping any medication, including Pirfenidone (Pirfenex). Follow your healthcare provider’s instructions for the proper use and dosage of the medication.